As the Corona Virus hit the world Earlier this year, it originated from the lab of Wuhan in China. Many countries affected due to this virus. People lose their lives because of this virus.
Countries had to go under lockdown in order to promote social distancing. In lockdown offices had to shut down, people are locked in their home.
Economy of many countries fell down due to Corona Virus and the world economy is facing another recession after the Financial crisis of 2007-2008.
How does Coronavirus affect the 16 million peoples Across the world?
It all started from one person and now getting worse day by day. Every country is facing this problem. But America, India and Brazil are the top 3 countries with the highest number of cases confirmed. So many people’s deaths have been recorded and now 16 million people have been affected by this.
Indian medical research icmr has now recorded the maximum covid-19 cases test positive in the last 24 hours. As the testing has increased to the maximum capacity.
We should make some serious majors to control the situation before it has adverse side effects.
Countries are now developing the possible corona vaccine
Government was funding many firms to develop a vaccine for this infectious disease because this is the best way to control the virus.
Now around 140 vaccine candidates are available around the world that were under the clinical trials or human trials.
Possible Corona Virus vaccine through the world
Vaccines have to go under various tests before it is approved for the production and use in the large scale vaccination for which they have to do clinical trials. After the successful clinical trials the vaccine will go under human trials which is done in three phases.
In the phase 1 the vaccine and a placebo controlled injection is given to a small group of volunteers of different ages to check if any side effects are not related with the vaccine and placebo injection is used to determine the study.
After the successful completion of phase 1 the vaccine will go under phase 2 where it is given to fairly large peoples to check the vaccine effectiveness in people. The condition of people of the diseased people will be student to determine the common short term effects related to the vaccine.
Phase 3 is basically a large group of people usually ranging from 1000 to 3000 participants have given the dose of vaccine to evaluate the overall risk and benefits. The Food and Drug reviews results from phase 3 and approve for mass production.
Some Corona Virus vaccine that are under Human trials
Of the 140 possible vaccine candidates 19 vaccines are under phase 1 trial, 13 are in phase 2 trials, 4 are in phase 3 trials and 1 vaccine is approved for limited use.
Scientists and Governments are racing the process of vaccine making to get the vaccine as early as possible. 27 vaccines are in human trials.
The work began in January with the founding of sars cov-2. The human trials started in march but the road ahead is uncertain.
Here is the status of all the vaccine that shows promising results under human trials:
The Indian company Bharat Biotech and ICMR coronavirus vaccine candidate started the trials and will take place in at least three stages.
The first phase will study the sample of 375 healthy persons of different ages over a trial period of 4-6 weeks . The stage two of the trial will cover the sample of 750 persons and the third trial covers around 1800 people.
After the successful trial results the vaccine could be ready before the end of this year.
This is the most potential vaccine after the results of the first phase were out. It shows positive results generating both antibodies and T-cells which act as immune system boosters.
The Indian company Serum Institute of India has said it will produce half the vaccine.
The experimental covid-19 vaccine that is under development by Germany and US firms. On monday said that the vaccine given to 60 people showed it was safe. And induced an immune response in patients. The firm also stated that there is also a high level of induction of t-cells.
Another indian vaccine candidate. Drugs controller General of India has allowed Zydus Cadila Healthcare Ltd for phase 1 and phase 2 trials. Company stated that it will take 7 months to complete the clinical trials after the phase 1 of trial starts.
The vaccine funded by the American President has dubbed the mRNA-1273. This led to the production of antibodies that helps to neutralise the coronavirus found in the vaccine trial. But it led to minor side effects in many patients like fever and body pain. The researcher said that it can be controlled by taking Paracetamol.
Sinovac Biotech’s CoronaVac
The Nasdaq Listed Chinese pharma firm has moved to phase 3 trials in Brazil. With two doses of vaccine including neutralizing antibodies after 14 days. It approved a deal with Brazilian medical science company to run the phase three trials in Brazil. Bangladesh also approved the last stage trials in their country.
So when do we get the Corona Virus vaccine
Oxford vaccine raced to top contender in all the vaccines to be approved for the treatment of corona patients.
And India is going to play a big part in this. Because Oxford partnered with the Serum Institute of India for the production of the vaccine. The CEO Adar Poonawalla stated: the firm will one billion doses in the coming year for india and low-and-middle-income countries. After the success of trials and licensure trials. He also stated that the price would be under Rs.1000.